=?iso-8859-2?Q?IJS_KOLOKVIJ=2C_sreda=2C_06._03_.2013; _ob_13._uri; _prof._d?= r. Antonio Šiber

[Barbara Hrovatin]

Vabimo vas na 10. predavanje iz sklopa "Kolokviji na IJS" v letu 2012/13, ki
bo v sredo, 6. marca 2013, ob 13. uri v Veliki predavalnici Instituta >Jožef
Stefan< na Jamovi cesti 39 v Ljubljani. Napovednik predavanja najdete tudi
na naslovu http://www.ijs.si/ijsw/Koledar_prireditev, posnetke preteklih
predavanj pa na http://videolectures.net/kolokviji_ijs.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~



prof. dr. Antonio Šiber

Inštitut za fiziko, Zagreb, Hrvaška

 

Nekaj fizike virusov in težka vprašanja brez odgovorov

 

Sedemdeset let potem, ko se je Schrödinger vprašal "Kaj je življenje?",
vemo, da je življenje nekaj, kar je povezano z informacijami. A vprašanje,
kako so "neživo snov" prepojile informacije, je še težje od
Schrödingerjevega. Večina življenja je zapletenega, a vseeno obstajajo
razmeroma preprosti z informacijami napolnjeni kompleksi, ki združujejo dve
ključni molekuli življenja, tj. DNA (ali RNA) in proteine - virusi. Virusi
so nekako povezani z življenjem, saj se širijo, prilagajajo in spreminjajo
le v "živi snovi", a to, ali so živi ali ne, ni razjasnjeno. Tako so kot
nalašč za fizike, ki jih zanimajo vprašanja biologije, saj se lahko vsaj
pretvarjajo, da raziskujejo neko vrsto makromolekularnega kompleksa, ki se
ne razlikuje zelo od npr. mikrotubula, ta pa skoraj gotovo ni živ. Vseeno
tudi preproste fizikalne študije naposled vodijo do vprašanj, ki jih navadno
zastavljajo biologi: "Za kaj je to koristno?" ali "Od kod se je to sploh
vzelo?" Orisali bomo eno od možnih poti od fizikalnih študij strukture in
energije virusov do teh biološko zanimivih vprašanj - in sicer lastno. Ta je
vključevala raziskave oblike in elastičnosti virusov, elektrostatično
interakcijo v virusih ter vpliv fizikalnih interakcij na sestavljanje ali
razstavljanje virusov.

Predavanje bo v angleščini.

Lepo vabljeni!

 

*****

 

 

 

 

We invite you to the 10th Institute colloquium in the academic year 2012/13.
The colloquium will be held on Wednesday March 6, 2013 at 1 PM in the main
Institute lecture hall, Jamova 39, Ljubljana. To read the abstract click
http://www.ijs.si/ijsw/Koledar_prireditev. Past colloquia are posted on
http://videolectures.net/kolokviji_ijs.

 

********************************************

prof. dr. Antonio Šiber

Institute of physics, Zagreb, Croatia

 

Some physics of viruses and the grand questions still unanswered

 

Seventy years after Schrödinger asked "What is life?" we know that life is
something related to information. But how "non-living" matter became imbued
with information is even a toughest question than the one Schrodinger asked.
Most life is complicated, yet there are reasonably simple information-rich
complexes that combine the two hallmark molecules of life i.e. DNA (or RNA)
and protein - viruses. Viruses have something to do with life, since they
propagate, adapt and change (evolve) only in "living matter", yet whether
they themselves are alive or not is not a resolved issue. Thus, they present
a system perfectly suited for a physicist interested in questions of
biology, since she/he can at least pretend to be studying some sort of a
macromolecular complex, not really that different from e.g. microtubule,
which is almost certainly not alive. Yet, even such poor-physicist-minded
studies do eventually lead to questions that biologists typically ask, such
as "What is it good for?" or "How did it arise in the first place?". I will
illustrate one possible path from the physical studies of virus structure
and energetics to these, biologically relevant questions. The particular
path will be the one I walked through in my studies of viruses. These
include the studies of virus shapes and elasticity, the electrostatic
interactions in viruses, and the influence of physical interactions in
viruses on their (dis)assembly.

 

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