<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><head><meta http-equiv=Content-Type content="text/html; charset=iso-8859-2"><meta name=Generator content="Microsoft Word 14 (filtered medium)"><style><!--
/* Font Definitions */
@font-face
{font-family:SimSun;
panose-1:2 1 6 0 3 1 1 1 1 1;}
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:"\@SimSun";
panose-1:2 1 6 0 3 1 1 1 1 1;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
margin-bottom:.0001pt;
font-size:12.0pt;
font-family:"Times New Roman","serif";}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:blue;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:purple;
text-decoration:underline;}
span.EmailStyle17
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:windowtext;}
span.EmailStyle18
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle19
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle20
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle21
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle22
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle23
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle24
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle25
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle26
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle27
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle28
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle29
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle30
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle31
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle32
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle33
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle34
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle35
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle36
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle37
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle38
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle39
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle40
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle41
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle42
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle43
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle44
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle45
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle46
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle47
{mso-style-type:personal;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle48
{mso-style-type:personal-reply;
font-family:"Calibri","sans-serif";
color:#1F497D;}
.MsoChpDefault
{mso-style-type:export-only;
font-size:10.0pt;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:70.85pt 70.85pt 70.85pt 70.85pt;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal align=center style='text-align:center'>Vabimo vas na 10. predavanje iz sklopa "Kolokviji na IJS" v letu 2012/13, ki bo <strong><span style='color:red'>v sredo, 6. marca 2013, ob 13. uri </span></strong><span style='color:red'>v Veliki predavalnici Instituta »Jožef Stefan«</span> na Jamovi cesti 39 v Ljubljani. Napovednik predavanja najdete tudi na naslovu <a href="http://www.ijs.si/ijsw/Koledar_prireditev">http://www.ijs.si/ijsw/Koledar_prireditev</a>, posnetke preteklih predavanj<span style='color:blue'> </span>pa na <a href="http://videolectures.net/kolokviji_ijs">http://videolectures.net/kolokviji_ijs</a>.<o:p></o:p></p><p class=MsoNormal align=center style='text-align:center'>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~<br><br><o:p></o:p></p><p class=MsoNormal align=center style='text-align:center'><b>prof. dr. Antonio Šiber<o:p></o:p></b></p><p class=MsoNormal align=center style='text-align:center'><i>Inštitut za fiziko, Zagreb, Hrvaška<o:p></o:p></i></p><p class=MsoNormal align=center style='mso-margin-top-alt:auto;text-align:center'><b><span style='font-size:14.0pt;mso-fareast-language:SL'><o:p> </o:p></span></b></p><p class=MsoNormal align=center style='text-align:center'><b><span style='font-size:14.0pt'>Nekaj fizike virusov in težka vprašanja brez odgovorov<o:p></o:p></span></b></p><p class=MsoNormal align=center style='text-align:center'><span style='font-size:11.0pt;font-family:"Arial","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal align=center style='text-align:center'>Sedemdeset let potem, ko se je Schrödinger vprašal “Kaj je življenje?“, vemo, da je življenje nekaj, kar je povezano z informacijami. A vprašanje, kako so “neživo snov” prepojile informacije, je še težje od Schrödingerjevega. Večina življenja je zapletenega, a vseeno obstajajo razmeroma preprosti z informacijami napolnjeni kompleksi, ki združujejo dve ključni molekuli življenja, tj. DNA (ali RNA) in proteine – virusi. Virusi so nekako povezani z življenjem, saj se širijo, prilagajajo in spreminjajo le v “živi snovi”, a to, ali so živi ali ne, ni razjasnjeno. Tako so kot nalašč za fizike, ki jih zanimajo vprašanja biologije, saj se lahko vsaj pretvarjajo, da raziskujejo neko vrsto makromolekularnega kompleksa, ki se ne razlikuje zelo od npr. mikrotubula, ta pa skoraj gotovo ni živ. Vseeno tudi preproste fizikalne študije naposled vodijo do vprašanj, ki jih navadno zastavljajo biologi: “Za kaj je to koristno?” ali “Od kod se je to sploh vzelo?” Orisali bomo eno od možnih poti od fizikalnih študij strukture in energije virusov do teh biološko zanimivih vprašanj – in sicer lastno. Ta je vključevala raziskave oblike in elastičnosti virusov, elektrostatično interakcijo v virusih ter vpliv fizikalnih interakcij na sestavljanje ali razstavljanje virusov.<i><o:p></o:p></i></p><p class=MsoNormal align=center style='mso-margin-top-alt:auto;margin-bottom:12.0pt;text-align:center'>Predavanje bo v angleščini.<span style='mso-fareast-language:SL'><o:p></o:p></span></p><p class=MsoNormal align=center style='mso-margin-top-alt:auto;margin-bottom:12.0pt;text-align:center'><strong><span style='color:red'>Lepo vabljeni!</span></strong><strong><span style='font-weight:normal'><o:p></o:p></span></strong></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt'><strong><span style='font-size:16.0pt;color:black'><o:p> </o:p></span></strong></p><p class=MsoNormal align=center style='text-align:center'><b><span style='font-size:14.0pt;font-family:"Calibri","sans-serif";color:black'>*****</span></b><span style='font-size:14.0pt;font-family:"Calibri","sans-serif"'><o:p></o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span style='color:black'>We invite you to the 10th Institute colloquium in the academic year 2012/13. The colloquium will be held <b>on Wednesday March 6, 2013 at 1 PM</b> in <b>the main Institute</b></span><b><span style='color:#1F497D'> </span><span style='color:black'>lecture hall</span></b><span style='color:black'>, Jamova 39, Ljubljana. To read the abstract click </span><span style='color:#1F497D'><a href="http://www.ijs.si/ijsw/Koledar_prireditev">http://www.ijs.si/ijsw/Koledar_prireditev</a>. </span><span style='color:black'>Past colloquia are posted on</span><span style='color:#1F497D'> <a href="http://videolectures.net/kolokviji_ijs">http://videolectures.net/kolokviji_ijs</a>.<o:p></o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span style='color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal align=center style='margin-bottom:12.0pt;text-align:center'>********************************************<b><o:p></o:p></b></p><p class=MsoNormal align=center style='text-align:center'><b>prof. dr. Antonio Šiber<o:p></o:p></b></p><p class=MsoNormal align=center style='text-align:center'><i>Institute of physics, Zagreb, Croatia</i><i><span lang=SL><o:p></o:p></span></i></p><p class=MsoNormal align=center style='text-align:center'><b><span style='font-size:16.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal align=center style='text-align:center'><b><span style='font-size:16.0pt'>Some physics of viruses and the grand questions still unanswered</span></b><b><span style='font-size:16.0pt;mso-fareast-language:SL'><o:p></o:p></span></b></p><p class=MsoNormal align=center style='text-align:center'><o:p> </o:p></p><p class=MsoNormal align=center style='text-align:center'>Seventy years after Schrödinger asked „What is life?“ we know that life is something related to information. But how „non-living“ matter became imbued with information is even a toughest question than the one Schrodinger asked. Most life is complicated, yet there are reasonably simple information-rich complexes that combine the two hallmark molecules of life i.e. DNA (or RNA) and protein – viruses. Viruses have something to do with life, since they propagate, adapt and change (evolve) only in „living matter“, yet whether they themselves are alive or not is not a resolved issue. Thus, they present a system perfectly suited for a physicist interested in questions of biology, since she/he can at least pretend to be studying some sort of a macromolecular complex, not really that different from e.g. microtubule, which is almost certainly not alive. Yet, even such poor-physicist-minded studies do eventually lead to questions that biologists typically ask, such as „What is it good for?“ or „How did it arise in the first place?“. I will illustrate one possible path from the physical studies of virus structure and energetics to these, biologically relevant questions. The particular path will be the one I walked through in my studies of viruses. These include the studies of virus shapes and elasticity, the electrostatic interactions in viruses, and the influence of physical interactions in viruses on their (dis)assembly.<o:p></o:p></p><p class=MsoNormal align=center style='text-align:center'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p></div></body></html>