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<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:34.0pt;font-family:"Aptos",sans-serif;color:#105A97">VABILO<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#105A97">Nacionalni inštitut za biologijo Vas vabi, da se udeležite seminarja<o:p></o:p></span></p>
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<b><span lang="EN-US" style="font-size:18.0pt;font-family:"Aptos",sans-serif;color:#2A8C46;letter-spacing:.05pt">»Genetic and epigenetic controls governing life cycle transitions in the planktonic diatom Pseudo-nitzschia multistriata«</span></b><span lang="EN-US" style="font-size:18.0pt;font-family:"Aptos",sans-serif;color:#2A8C46;letter-spacing:.05pt">,<b><o:p></o:p></b></span></p>
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<span style="font-family:"Aptos",sans-serif;color:#105A97">ki ga bo predstavila<o:p></o:p></span></p>
<p class="Default" align="center" style="margin-bottom:4.0pt;text-align:center"><b><span style="font-size:18.0pt;font-family:"Aptos",sans-serif;color:#105A97">dr. Mariella Ferrante<o:p></o:p></span></b></p>
<p class="Default" align="center" style="text-align:center"><b><span style="font-family:"Aptos",sans-serif;color:#105A97">Senior Researcher at SZN and Associate to the National Institute
<o:p></o:p></span></b></p>
<p class="Default" align="center" style="text-align:center"><b><span style="font-family:"Aptos",sans-serif;color:#105A97">of Oceanography and Applied Geophysics<o:p></o:p></span></b></p>
<p class="Default" align="center" style="text-align:center"><b><span style="font-family:"Aptos",sans-serif;color:#105A97"><o:p> </o:p></span></b></p>
<p class="Default" align="center" style="text-align:center"><b><span style="font-size:34.0pt;font-family:"Aptos",sans-serif;color:#105A97"><img width="185" height="185" style="width:1.927in;height:1.927in" id="Picture_x0020_2" src="cid:image001.jpg@01DA4D44.7C807840" alt="A person smiling for a picture
Description automatically generated"></span></b><b><span style="font-size:16.0pt;font-family:"Aptos",sans-serif;color:#105A97"><o:p></o:p></span></b></p>
<p class="MsoNoSpacing"><span style="font-size:8.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:115%"><b><span style="font-size:13.0pt;line-height:115%;font-family:"Aptos",sans-serif;color:#2A8C46;letter-spacing:.05pt">Seminar bo v petek, 26. januarja 2024, ob 13. uri<o:p></o:p></span></b></p>
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<b><span style="font-size:13.0pt;font-family:"Aptos",sans-serif;color:#2A8C46;letter-spacing:.05pt">na Morski biološki postaji Piran, Fornače 41, Piran, v mali predavalnici in v okolju Webex:<o:p></o:p></span></b></p>
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<a href="https://us02web.zoom.us/j/84382424385?pwd=U3dUSmpmMmZvNTIvazYvNVF3WE41Zz09">https://us02web.zoom.us/j/84382424385?pwd=U3dUSmpmMmZvNTIvazYvNVF3WE41Zz09</a><o:p></o:p></p>
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<span class="MsoHyperlink"><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;letter-spacing:.05pt"><o:p><span style="text-decoration:none"> </span></o:p></span></span></p>
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<span lang="EN-US" style="font-family:"Aptos",sans-serif;color:#2A8C46;letter-spacing:.05pt">Meeting number: 843 8242 4385, Passcode: 556603</span><span lang="EN-US" style="color:#2A8C46"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><b><u><span style="color:#636363">Povzetek:<o:p></o:p></span></u></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-size:10.0pt;color:#636363">Phytoplankton dynamics are regulated by external cues, mainly light and nutrients, as well as by biotic interactions and endogenous controls linked to
life cycle characteristics. <o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-size:10.0pt;color:#636363">With few exceptions, sexual reproduction is an obligate phase in diatom life cycles, required to escape the miniaturization process imposed by the rigid
cell wall, as well as to generate genetic diversity. The planktonic pennate diatom Pseudo-nitzschia multistriata, with a heterothallic mating system with two opposite mating types (MTs), represents a model for the study of diatom life cycles. P. multistriata
is also a toxic diatom, being able to produce the neurotoxin domoic acid. <o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-size:10.0pt;color:#636363">Gene expression studies identified genes involved in the response to sexual clues and in the mechanism of sex determination. How exactly sex is determined
and what triggers competence for sex after a given cell size is reached are still open questions. To address these questions, we are exploring epigentic controls and are using advanced technologies, such as single cell RNA-seq, for the characterization of
MT specific genes and the gene networks in which they participate. I will also present recent results on the exploration of genomic diversity in P. multistriata populations, with a focus on the genes involved in the production of domoic acid.
<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:10.0pt;color:#636363"><o:p> </o:p></span></p>
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<strong><span style="font-size:11.0pt;font-family:"Aptos",sans-serif">Vljudno vabljeni! Seminar bo potekal v angleškem jeziku.<o:p></o:p></span></strong></p>
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<strong><span lang="EN-US" style="font-size:11.0pt;font-family:"Aptos",sans-serif;color:#0C3512">You are cordially invited to attend this lecture, which will be held in English.<o:p></o:p></span></strong></p>
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<span style="font-size:8.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="font-family:"Aptos",sans-serif;color:#636363">Dodatne informacije: Dr. Timotej Turk Dermastia,
</span><a href="mailto:Timotej.TurkDermastia@nib.si"><span style="font-family:"Aptos",sans-serif">Timotej.TurkDermastia@nib.si</span></a><span style="font-size:10.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#0563C1;mso-fareast-language:SL"><o:p><span style="text-decoration:none"> </span></o:p></span></u></p>
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