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<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif"">Vabilo na Preglov kolokvij / Invitation to the Pregl colloquium<o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:12.0pt;font-family:"Arial Narrow","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-family:"Arial Narrow","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:20.0pt;font-family:"Arial Narrow","sans-serif"">Assoc. Prof. Giovanni Maglia
<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif"">University of Groningen, Groningen, Netherlands<o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif"">Email:
</span><a href="mailto:g.maglia@rug.nl" target="_blank"><span style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif"">g.maglia@rug.nl</span></a><span style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif""><o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:20.0pt;font-family:"Arial Narrow","sans-serif"">Četrtek / Thursday 13. 4. 2017, ob / at 13:00
<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:16.0pt;font-family:"Arial Narrow","sans-serif""><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif"">Velika predavalnica Kemijskega inštituta / Great Lecture Hall, National Institute of Chemistry;
<o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif"">Hajdrihova 19, Ljubljana<b><o:p></o:p></b></span></p>
<p class="EndNoteBibliography" style="margin-bottom:0cm;margin-bottom:.0001pt"><span lang="EN-US" style="font-size:9.0pt;font-family:"Arial Narrow","sans-serif";color:#660066"><o:p> </o:p></span></p>
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<b><span lang="EN-US" style="font-size:16.0pt;font-family:"Arial Narrow","sans-serif";color:#792D4C"><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:20.0pt;font-family:"Tahoma","sans-serif"">Harnessing nanopores for single-molecule enzymology and protein sequencing<o:p></o:p></span></b></p>
<p class="MsoNormal" style="layout-grid-mode:char"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif";color:#792D4C"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-family:"Arial Narrow","sans-serif"">Biological nanopores are a class of membrane proteins that form nanometer-size apertures on lipid membranes. Under an applied potential the ionic
current through nanopores is used to identify molecules or to follow reactions at the single-molecule level. Nanopores current are advantageous because they are easily integrated into low-cost and portable analytical devices.</span><span lang="EN-US" style="font-size:12.0pt;font-family:"Arial Narrow","sans-serif""><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-family:"Arial Narrow","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-family:"Arial Narrow","sans-serif"">Here we show that the transport of proteins and peptides across nanopores can be finely controlled. Folded proteins can trapped inside nanopores
by exploiting electrophoretic forces, while small peptides can be stretched and unfolded by engineering strong electroosmotic flows through the nanopore. Using these approaches, nanopores may be used as nanoscale reactor for single-molecule enzymology studies,
or sensors for sequencing individual proteins as they translocate across the nanopore.
<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:14.0pt;font-family:"Arial Narrow","sans-serif"">info:
<a href="mailto:gregor.anderluh@ki.si">gregor.anderluh@ki.si</a><o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:14.0pt"><b><span style="font-size:10.0pt;font-family:"Open Sans";color:#6B6B6E;mso-fareast-language:SL">Brigita Pirc</span></b><b><span style="mso-fareast-language:SL"><o:p></o:p></span></b></p>
<p class="MsoNormal" style="line-height:14.0pt"><span style="font-size:10.0pt;font-family:"Open Sans";color:#6B6B6E;mso-fareast-language:SL">Odnosi z javnostmi /
<i>Public Relations</i></span><span style="font-size:12.0pt;mso-fareast-language:SL"><o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:13.0pt"><span style="font-size:10.0pt;font-family:"Open Sans";color:#6B6B6E;mso-fareast-language:SL">Kemijski inštitut /
<i>National Institute of Chemistry </i></span><span style="mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:13.0pt"><span style="font-size:10.0pt;font-family:"Open Sans";color:#6B6B6E;mso-fareast-language:SL">Hajdrihova 19</span><span style="mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:13.0pt"><span style="font-size:10.0pt;font-family:"Open Sans";color:#6B6B6E;mso-fareast-language:SL">SI-1000 Ljubljana</span><span style="mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:13.0pt"><span style="font-size:10.0pt;font-family:"Open Sans";color:#6B6B6E;mso-fareast-language:SL">Slovenija /
<i>Slovenia</i></span><span style="mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:13.0pt"><span style="font-size:10.0pt;font-family:"Open Sans";color:#6B6B6E;mso-fareast-language:SL">Telefon / Phone: 00386 1 476 02 25</span><span style="mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:13.0pt"><span style="font-size:10.0pt;font-family:"Open Sans";color:#8DB3E2;mso-fareast-language:SL"><a href="mailto:brigita.pirc@ki.si"><span style="color:#8DB3E2">brigita.pirc@ki.si</span></a></span><span style="font-size:10.0pt;font-family:"Open Sans";color:#6888BD;mso-fareast-language:SL">
</span><span style="mso-fareast-language:SL"><a href="http://www.ki.si/"><span style="font-size:10.0pt;font-family:"Open Sans";color:#6888BD">www.ki.si</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;mso-fareast-language:SL"> </span><span style="font-size:12.0pt;mso-fareast-language:SL"><o:p></o:p></span></p>
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