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<p class="Heading" style="margin:0cm;margin-bottom:.0001pt"><span style="font-size:18.0pt;font-family:"Candara","sans-serif";color:black;font-weight:normal">VABILO NA PREDSTAVITEV ODKRITJA</span><span style="font-size:20.0pt;font-family:"Candara","sans-serif""><o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:9.0pt;font-family:"Candara","sans-serif""><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:115%"><b><span style="font-size:18.0pt;line-height:115%;font-family:"Candara","sans-serif";color:#C00000">ODKRITJE GENA ZA VITKOST ODPIRA NOVE MOŽNOSTI TERAPIJE ZA Z DEBELOSTJO POVEZAN
DIABETES<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-family:"Candara","sans-serif""><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:24.0pt;font-family:"Candara","sans-serif"">prof. dr. Simon Horvat<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><i><span lang="EN-US" style="font-size:8.0pt;font-family:"Candara","sans-serif""><o:p> </o:p></span></i></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:150%"><b><span style="font-size:20.0pt;line-height:150%;font-family:"Candara","sans-serif";color:black">v sredo 15. 06. 2016 ob 12:00</span></b><b><span lang="FR" style="font-size:20.0pt;line-height:150%;font-family:"Candara","sans-serif";color:black"><o:p></o:p></span></b></p>
<h6 style="margin:0cm;margin-bottom:.0001pt"><b><span lang="EN-GB" style="font-size:20.0pt;font-family:"Candara","sans-serif";color:black">Velika predavalnica Kemijskega inštituta
</span></b><span lang="EN-GB"><o:p></o:p></span></h6>
<p class="MsoNormal"><span lang="EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="FR" style="font-size:14.0pt;font-family:"Candara","sans-serif";color:black"><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="FR" style="font-size:14.0pt;font-family:"Candara","sans-serif";color:black">Svojo razlago k dosežku bo podal tudi<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="FR" style="font-size:8.0pt;font-family:"Candara","sans-serif";color:black"><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="FR" style="font-size:16.0pt;font-family:"Candara","sans-serif";color:#C00000">prof. dr. Tadej Battelino, dr. med.<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="FR" style="font-size:14.0pt;font-family:"Candara","sans-serif";color:black">predstojnik Kliničnega oddelka za endokrinologijo, diabetes in bolezni presnove (Univerzitetni klinični
center Ljubljana)<o:p></o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><b><span lang="EN-GB" style="font-size:18.0pt;font-family:"Candara","sans-serif";color:#993366"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="FR" style="font-size:14.0pt;font-family:"Candara","sans-serif";color:black">Zaradi naraščajoče globalne epidemije debelosti (»globelost«), in z njo povezanimi zdravstvenimi zapleti kot je sladkorna
bolezen tipa 2, so se v zadnjem desetletju znanstveniki osredotočali predvsem na iskanje genov, ki povečajo tveganje za razvoj debelosti. Slovenski raziskovalci z vodilnim avtorjem raziskave prof. Simonom Horvatom (Kemijski Inštitut in Biotehniška fakulteta,
Univerza v Ljubljani) in sodelavci iz Škotske (Univerza v Edinburgu) pa se je v tej študiji osredotočila na iskanje genov za »vitkost«. Odkrili so pomemben nov gen imenovan TST (tiosulfat-sulfur-transferaza), ki je pri višjem izražanju v maščobnem tkivu v
živalskih modelih povzročal odpornost na razvoj debelosti in diabetesa tudi v pogojih hranjenja z visoko kalorično hrano. Še več, tudi pri ljudeh so pokazali, da je nivo TST povišan v maščobnem tkivu vitkih in zdravih ljudi in znižan pri debelih in diabetičnih
bolnikih. S stimulacijo gena TST so lahko zmanjšali negativne učinke diabetesa pri živalskem modelu. Pričakujejo, da bo v prihodnje z iskanjem učinkovitejših farmakoloških učinkovin ali uporabo sodobne sintezne biologije, možno razviti komplementarne terapije
za z debelostjo povezano sladkorno bolezen.<o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:14.0pt;font-family:"Candara","sans-serif";mso-fareast-language:SL"><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:14.0pt;font-family:"Candara","sans-serif";mso-fareast-language:SL">Vljudno vabljeni!
<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:14.0pt;font-family:"Candara","sans-serif";mso-fareast-language:SL"><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:14.0pt;font-family:"Candara","sans-serif";mso-fareast-language:SL"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><span lang="FR" style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><b><span style="font-family:"Arial","sans-serif";color:#990033;mso-fareast-language:SL">Brigita Pirc</span></b><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><img width="56" height="32" id="Picture_x0020_3" src="cid:image001.jpg@01D1C169.AE59C2A0" alt="Description: Description: Description: LOGO EPRUVETE ki">
<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">Kemijski inštitut</span><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL">
<br>
</span><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">Hajdrihova 19</span><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><br>
</span><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">SI-1001 Ljubljana
<br>
Tel.: + 386 /1/ 4760 - 225<br>
Fax: + 386 /1/ 4760 - 300</span><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><br>
</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><a href="http://www.ki.si/"><span style="font-size:9.0pt;font-family:"Arial","sans-serif"">http://www.ki.si/</span></a></span><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">
</span><span style="font-size:9.0pt;color:#1F497D;mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-size:7.5pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">Kemijski inštitut je javni raziskovalni zavod, ki opravlja javno službo na področju znanstvene in raziskovalno-razvojne dejavnosti. Katalog informacij javnega
značaja je dostopen na spletnem naslovu </span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><a href="http://www.ki.si/o-institutu/katalog-ijz"><span style="font-size:7.5pt;font-family:"Arial","sans-serif"">www.ki.si/o-institutu/katalog-ijz</span></a></span><span style="font-size:7.5pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-size:7.5pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">To sporočilo in vsi pripeti dokumenti so zaupni in namenjeni izključno naslovniku. Če vam sporočilo ni bilo namenjeno, ni dovoljeno razkrivanje, nadaljnje pošiljanje
ali drugačna uporaba oziroma predelava posredovanih informacij. V tem primeru vas prosimo, da obvestite pošiljatelja in sporočilo izbrišete. Kemijski inštitut ne prevzema odgovornosti za napake v prenosu.</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:32.0pt;font-family:Webdings;color:green;mso-fareast-language:SL">P</span><span style="font-family:"Verdana","sans-serif";color:green;mso-fareast-language:SL">
</span><span style="font-size:8.0pt;font-family:"Arial","sans-serif";color:green;mso-fareast-language:SL">Morate res natisniti to sporočilo? Mislite zeleno.</span><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:green;mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="FR" style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p> </o:p></span></p>
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<p class="MsoNormal"><span lang="FR" style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p> </o:p></span></p>
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