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<p class="MsoTitle" style="margin:0cm;margin-bottom:.0001pt"><span style="font-family:"Verdana","sans-serif";color:black;font-weight:normal">Vabilo na predavanje / Invitation to the lecture<o:p></o:p></span></p>
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<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:18.0pt;font-family:"Verdana","sans-serif""><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:18.0pt;font-family:"Verdana","sans-serif"">Prof. Alessandra Magistrato
<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><i><span lang="EN-US" style="font-size:12.0pt;font-family:"Calibri","sans-serif""><o:p> </o:p></span></i></p>
<p class="MsoNormal" align="center" style="margin-bottom:12.0pt;text-align:center;line-height:19.0pt">
<span lang="FR" style="font-size:14.0pt;font-family:"Calibri","sans-serif";mso-fareast-language:ZH-CN">CNR IOM and International School for Advanced Studies, Trieste. Italy<o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:150%"><b><span style="font-size:16.0pt;line-height:150%;font-family:"Verdana","sans-serif""><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:150%"><b><span style="font-size:16.0pt;line-height:150%;font-family:"Verdana","sans-serif"">ponedeljek / Monday, 9. 5. 2016, ob / at 13:00<o:p></o:p></span></b></p>
<h6 style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm">
<b><span lang="EN-US" style="font-size:11.0pt;font-family:"Verdana","sans-serif"">Velika predavalnica Kemijskega inštituta / Lecture Hall at the National Institute of Chemistry; Hajdrihova 19, Ljubljana</span></b><b><span lang="EN-US" style="font-size:12.0pt;font-family:"Verdana","sans-serif"">
<o:p></o:p></span></b></h6>
<p class="MsoTitle" style="margin:0cm;margin-bottom:.0001pt"><span lang="EN-GB" style="font-size:14.0pt;mso-fareast-language:EN-US;font-weight:normal"><o:p> </o:p></span></p>
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<b><span lang="EN-GB" style="font-size:16.0pt;font-family:"Verdana","sans-serif";color:#993366">Computational Studies of Biological Systems Related to Human Diseases<o:p></o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-size:8.0pt;font-family:"Calibri","sans-serif""><o:p> </o:p></span></p>
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<span lang="ZH-CN" style="font-size:16.0pt;font-family:"MS Mincho";mso-fareast-language:ZH-CN">
</span><span lang="ZH-CN" style="font-size:16.0pt;font-family:"Cambria","serif";mso-fareast-language:ZH-CN">
</span><span lang="EN-US" style="font-size:14.0pt;font-family:"Calibri","sans-serif"">Computational biology is playing an ever increasing important role in understanding at atomistic level of detail the complex mechanisms of biological processes, complementing
experimental data and predicting novel aspects of those processes, which are inaccessible to experiments. In this talk multi scale simulations ranging from force field based molecular dynamics to hybrid quantum classical (QM/MM) simulations, in combination
with state of the art advanced sampling techniques, will be used to understand the molecular mechanisms of biological processes related to human diseases. In particular, I will focus on enzymes metabolizing hormones, on self splicing ribozymes, on DNA repair
enzymes, and finally, on membrane proteins, which transport nutrients across the cellular membranes</span><span lang="FR" style="font-size:16.0pt;font-family:"Cambria","serif";mso-fareast-language:ZH-CN">.
</span><span lang="FR" style="font-family:"Times","serif";mso-fareast-language:ZH-CN"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="FR"> </span><span lang="EN-GB" style="font-size:8.0pt;font-family:"Arial","sans-serif";color:#333333"><o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:12.0pt;font-family:"Arial","sans-serif";mso-fareast-language:SL">Vljudno vabljeni! / Kindly invited!<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:12.0pt;font-family:"Arial","sans-serif";mso-fareast-language:SL"><o:p> </o:p></span></b></p>
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<span lang="FR" style="font-size:11.0pt;line-height:150%;font-family:"Verdana","sans-serif"">Info:
</span><span lang="EN-GB" style="font-size:11.0pt;line-height:150%;font-family:"Verdana","sans-serif";color:black;mso-fareast-language:SL">Janez Mavri,
<a href="mailto:janez.mavri@ki.si">janez.mavri@ki.si</a></span><span lang="EN-GB" style="font-size:11.0pt;line-height:150%;font-family:"Verdana","sans-serif";mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><img border="0" width="56" height="32" id="Picture_x0020_3" src="cid:image001.jpg@01D1A5E7.6F1E9A40" alt="Description: Description: Description: LOGO EPRUVETE ki">
<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">Kemijski inštitut</span><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL">
<br>
</span><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">Hajdrihova 19</span><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><br>
</span><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">SI-1001 Ljubljana</span><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL">
<br>
</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><a href="http://www.ki.si/"><span style="font-size:9.0pt;font-family:"Arial","sans-serif"">http://www.ki.si/</span></a></span><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">
</span><span style="font-size:9.0pt;color:#1F497D;mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-size:7.5pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">Kemijski inštitut je javni raziskovalni zavod, ki opravlja javno službo na področju znanstvene in raziskovalno-razvojne dejavnosti. Katalog informacij javnega
značaja je dostopen na spletnem naslovu </span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><a href="http://www.ki.si/o-institutu/katalog-ijz"><span style="font-size:7.5pt;font-family:"Arial","sans-serif"">www.ki.si/o-institutu/katalog-ijz</span></a></span><span style="font-size:7.5pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-size:7.5pt;font-family:"Arial","sans-serif";color:#1F497D;mso-fareast-language:SL">To sporočilo in vsi pripeti dokumenti so zaupni in namenjeni izključno naslovniku. Če vam sporočilo ni bilo namenjeno, ni dovoljeno razkrivanje, nadaljnje pošiljanje
ali drugačna uporaba oziroma predelava posredovanih informacij. V tem primeru vas prosimo, da obvestite pošiljatelja in sporočilo izbrišete. Kemijski inštitut ne prevzema odgovornosti za napake v prenosu.</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:32.0pt;font-family:Webdings;color:green;mso-fareast-language:SL">P</span><span style="font-family:"Verdana","sans-serif";color:green;mso-fareast-language:SL">
</span><span style="font-size:8.0pt;font-family:"Arial","sans-serif";color:green;mso-fareast-language:SL">Morate res natisniti to sporočilo? Mislite zeleno.</span><span style="font-size:9.0pt;font-family:"Arial","sans-serif";color:green;mso-fareast-language:SL"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
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<span lang="FR" style="font-size:11.0pt;line-height:150%;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
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