<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><head><meta http-equiv=Content-Type content="text/html; charset=iso-8859-2"><meta name=Generator content="Microsoft Word 15 (filtered medium)"><style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:DengXian;
panose-1:2 1 6 0 3 1 1 1 1 1;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:"\@DengXian";
panose-1:2 1 6 0 3 1 1 1 1 1;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
margin-bottom:.0001pt;
font-size:11.0pt;
font-family:"Calibri",sans-serif;
mso-fareast-language:EN-US;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#0563C1;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:#954F72;
text-decoration:underline;}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Calibri",sans-serif;
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;
font-family:"Calibri",sans-serif;
mso-fareast-language:EN-US;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:70.85pt 70.85pt 70.85pt 70.85pt;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]--></head><body lang=SL link="#0563C1" vlink="#954F72"><div class=WordSection1><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>Vabimo vas na 11. predavanje iz sklopa "Kolokviji na IJS" v letu 2018/19, ki bo <b><span style='color:red'>v torek, 26. marca 2019, ob 13.30 uri </span></b><span style='color:red'>v Veliki predavalnici Instituta »Jožef Stefan«</span> na Jamovi cesti 39 v Ljubljani. Napovednik predavanja najdete tudi na naslovu <a href="http://www.ijs.si/ijsw/Koledar_prireditev">http://www.ijs.si/ijsw/Koledar_prireditev</a>, posnetke preteklih predavanj<span style='color:blue'> </span>pa na <a href="http://videolectures.net/kolokviji_ijs">http://videolectures.net/kolokviji_ijs</a>. <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~<br><br><b><span style='color:red'><o:p></o:p></span></b></span></p><p class=MsoNormal><b><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>Prof. dr. Rosario Rizzuto</span></b><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'><o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><i><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>rektor Univerze v Padovi, oddelek za biomedicinske znanosti, Italija<o:p></o:p></span></i></p><p class=MsoNormal style='text-align:justify'><i><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'><o:p> </o:p></span></i></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt;text-align:justify'><b><span style='font-size:14.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>Mitohondriji in signaliziranje preko kalcijevih ionov - vpliv na življenje in smrt celic<o:p></o:p></span></b></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt;text-align:justify'><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>Mitohondrijski uniporter za kalcijeve ione (MCU) je ključen protein pri transportu kalcijevih ionov v mitohondrijski matriks, preko tega pa vpliva na signaliziranje preko kalcija na splošno ter tudi uravnava aerobni metabolizem oziroma celično smrt preko apoptoze. Razkritje teh mehanizmov na molekulskem nivoju in uporaba MCU kot tarče in vivo bo bistveno prispevalo k razumevanju teh procesov, ključnih tako za normalno delovanje celic kot tudi pri razvoju bolezni.<o:p></o:p></span></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt;text-align:justify'><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>Predavanje bo v angleščini.<o:p></o:p></span></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt'><b><span style='font-size:12.0pt;font-family:"Times New Roman",serif;color:red;mso-fareast-language:SL'>Lepo vabljeni!<o:p></o:p></span></b></p><p class=MsoNormal align=center style='text-align:center'><span style='color:black;mso-fareast-language:SL'>*****<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'><o:p> </o:p></span></p><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'><br clear=all style='page-break-before:always'></span><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman",serif;color:black;mso-fareast-language:SL'>We invite you to the 11th Institute colloquium in the academic year 2018/19. The colloquium will be held </span><b><span style='font-size:12.0pt;font-family:"Times New Roman",serif;color:red;mso-fareast-language:SL'>on Tuesday March 26, 2019 at 13:30 PM</span></b><span style='font-size:12.0pt;font-family:"Times New Roman",serif;color:red;mso-fareast-language:SL'> in <b>the main Institute lecture hall</b></span><span style='font-size:12.0pt;font-family:"Times New Roman",serif;color:black;mso-fareast-language:SL'>, Jamova 39, Ljubljana. To read the abstract click </span><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'><a href="http://www.ijs.si/ijsw/Koledar_prireditev">http://www.ijs.si/ijsw/Koledar_prireditev</a><span style='color:#1F497D'>. </span><span style='color:black'>Past colloquia are posted on</span><span style='color:#1F497D'> </span><a href="http://videolectures.net/kolokviji_ijs">http://videolectures.net/kolokviji_ijs</a><span style='color:#1F497D'>.<o:p></o:p></span></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>********************************************<b><o:p></o:p></b></span></p><p class=MsoNormal><b><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>Prof. dr. Rosario Rizzuto<o:p></o:p></span></b></p><p class=MsoNormal><i><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>Rector University of Padua, Department of Biomedical Sciences, Italy<o:p></o:p></span></i></p><p class=MsoNormal><i><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'><o:p> </o:p></span></i></p><p class=MsoNormal style='text-autospace:none'><b><span lang=EN-US style='font-size:12.0pt;font-family:"Arial",sans-serif;color:black;mso-fareast-language:ZH-CN'>Mitochondria calcium signalling in cell life and death<o:p></o:p></span></b></p><p class=MsoNormal style='text-autospace:none'><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman",serif;color:black;mso-fareast-language:ZH-CN'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>The Mitochondrial Calcium Uniporter (MCU) mediates Ca2+ transport inside the organelle matrix, thus shaping global calcium signals and controlling either aerobic metabolism or cell death through apoptosis. The molecular elucidation and in vivo targeting of the MCU complex is now revealing new information on the role of mitochondrial Ca2+ signaling in health and disease.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:SL'>Cordially invited!<o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p></div></body></html>