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<p class="MsoTitle" style="margin:0cm;margin-bottom:.0001pt"><span lang="EN-US" style="font-size:14.0pt;font-family:"Verdana","sans-serif";font-weight:normal"><o:p> </o:p></span></p>
<p class="MsoTitle" style="margin:0cm;margin-bottom:.0001pt"><span lang="EN-US" style="font-size:14.0pt;font-family:"Verdana","sans-serif";font-weight:normal">VABILO NA PREDAVANJE / INVITATION TO THE LECTURE<o:p></o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:12.0pt;font-family:"Verdana","sans-serif""><o:p> </o:p></span></b></p>
<p align="center" style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:12.0pt;margin-left:0cm;text-align:center">
<b><span lang="EN-US" style="font-size:18.0pt;font-family:"Verdana","sans-serif"">Prof. Martin Rumbo, Ph.D.</span></b><span lang="EN-GB" style="font-size:8.0pt;font-family:"Verdana","sans-serif""><o:p></o:p></span></p>
<p align="center" style="margin:0cm;margin-bottom:.0001pt;text-align:center"><span lang="EN-GB" style="font-size:12.0pt;font-family:"Verdana","sans-serif"">National University of La Plata (UNLP), National Research Council (CONICET), Argentina<o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:8.0pt;font-family:"Verdana","sans-serif";mso-fareast-language:SL"><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:150%"><b><span lang="EN-US" style="font-size:8.0pt;line-height:150%;font-family:"Verdana","sans-serif""><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:150%"><b><span style="font-size:14.0pt;line-height:150%;font-family:"Verdana","sans-serif"">Ponedeljek</span></b><b><span lang="EN-US" style="font-size:14.0pt;line-height:150%;font-family:"Verdana","sans-serif"">
/ Monday 13. 07. 2015, </span></b><b><span style="font-size:14.0pt;line-height:150%;font-family:"Verdana","sans-serif"">ob</span></b><b><span lang="EN-US" style="font-size:14.0pt;line-height:150%;font-family:"Verdana","sans-serif""> / at 12:00
<o:p></o:p></span></b></p>
<h6 style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm">
<b><span style="font-size:11.0pt;font-family:"Verdana","sans-serif"">Velika predavalnica Kemijskega inštituta</span></b><b><span lang="EN-US" style="font-size:11.0pt;font-family:"Verdana","sans-serif""> / Lecture Hall at the National Institute of Chemistry;
Hajdrihova 19, Ljubljana</span></b><b><span lang="EN-US" style="font-size:12.0pt;font-family:"Verdana","sans-serif"">
<o:p></o:p></span></b></h6>
<p class="MsoNormal" style="mso-margin-top-alt:6.0pt;margin-right:0cm;margin-bottom:6.0pt;margin-left:0cm;text-align:justify">
<b><span lang="EN-US" style="font-size:9.0pt;font-family:"Verdana","sans-serif";color:#993366"><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-GB" style="font-size:20.0pt;font-family:"Verdana","sans-serif";color:#660066">Use of TLR-ligand interaction to generate immunomodulators and adjuvants</span></b><b><span lang="EN-GB" style="font-size:20.0pt;font-family:"Verdana","sans-serif";color:#1F497D">
</span></b><b><span lang="EN-GB" style="font-size:20.0pt;font-family:"Verdana","sans-serif";color:#660066"><o:p></o:p></span></b></p>
<p class="EndNoteBibliography" align="center" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:center">
<span lang="EN-US" style="font-size:9.0pt;font-family:"Verdana","sans-serif";color:#660066"><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="EN-US" style="font-size:11.0pt;font-family:"Arial","sans-serif"">TLRs as prototypical receptors of innate immunity has a great capacity to recognize diverse ligands with a conserved canonical
structure. Different TLR have a spectrum of recognition of distinct molecular patterns. Enhancing or blocking TLR signaling can be envisaged for adjuvant or anti-inflammatory effects respectively. The generation of a fusion protein between
<i>Brucella</i> lumazine sinthetase and <i>Salmonella</i> flagellin will be discussed. This fusion protein forms a decameric structure with antigen carriage capacity. Furthermore, the generation of low molecular weight peptide agonists to TLR5 will also be
discussed.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="FR"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="FR"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="FR"><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:150%"><b><span style="font-size:14.0pt;line-height:150%;font-family:"Verdana","sans-serif"">Vljudno vabljeni!</span></b><b><span lang="EN-US" style="font-size:14.0pt;line-height:150%;font-family:"Verdana","sans-serif"">
/ Kindly invited!<o:p></o:p></span></b></p>
<p class="MsoNormal"><span lang="FR"><o:p> </o:p></span></p>
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