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<span style="font-size:12.0pt;font-family:"Verdana","sans-serif";color:black;font-weight:normal">***<o:p></o:p></span></p>
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<span style="font-family:"Verdana","sans-serif";color:black">VABILO NA PREGLOV KOLOKVIJ / INVITATION TO THE PREGL COLLOQUIUM<o:p></o:p></span></p>
<p class="MsoNormal"><b><span style="font-size:8.0pt;font-family:"Verdana","sans-serif""><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><b><span style="font-size:18.0pt;font-family:"Verdana","sans-serif";mso-fareast-language:SL">Prof. dr. Arthur Olson,
</span></b><span lang="FR" style="font-size:11.0pt;font-family:"Verdana","sans-serif"">Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="IT" style="font-size:8.0pt;font-family:"Arial","sans-serif";mso-fareast-language:SL"><o:p> </o:p></span></p>
<p class="MsoNormal" style="line-height:150%"><b><span style="font-size:16.0pt;line-height:150%;font-family:"Verdana","sans-serif"">Četrtek / Thursday, 06. 09. 2012, ob / at 13:00<o:p></o:p></span></b></p>
<h6 align="left" style="margin:0cm;margin-bottom:.0001pt;text-align:left"><b><span lang="FR" style="font-size:11.0pt;font-family:"Verdana","sans-serif"">Velika predavalnica Kemijskega inštituta / Lecture Hall at the National Institute of Chemistry; Hajdrihova
19, Ljubljana<o:p></o:p></span></b></h6>
<p class="MsoNormal"><span lang="FR"><o:p> </o:p></span></p>
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<p class="MsoNormal" style="margin-bottom:6.0pt"><b><span lang="EN-GB" style="font-size:20.0pt;font-family:"Verdana","sans-serif";color:#993366">Interacting with Protein Interactions<o:p></o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><b><span lang="EN-GB" style="font-size:8.0pt;font-family:"Verdana","sans-serif";color:#993366">Abstract:<o:p></o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><span lang="FR" style="font-size:11.0pt;font-family:"Arial","sans-serif"">Biology has become accessible to an understanding of processes that span from atom to organism. As such we now have the opportunity to
build a spatio-temporal picture of living systems at the molecular level. In our recent work we attempt to create, interact with, and communicate physical representations of complex molecular environments. I will discuss and demonstrate three levels of interaction
with protein interactions: 1) human perceptual and cognitive interaction with complex structural information; 2) interaction and integration of multiple data sources to construct cellular environments at the molecular level; and 3) interaction of software
tools that can bridge the disparate disciplines needed to explore, analyze and communicate a holistic molecular view of living systems.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><span lang="FR" style="font-size:11.0pt;font-family:"Arial","sans-serif"">In order to increase our understanding and interaction with complex molecular structural information we have combined two evolving computer
technologies, solid printing and augmented reality. We create custom tangible molecular models and track their manipulation with real-time video, superimposing text and graphics onto the models to enhance their information content and to drive interactive
computation.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><span lang="FR" style="font-size:11.0pt;font-family:"Arial","sans-serif"">We have recently developed automated technologies to construct the crowded molecular environment of living cells from structural information
at multiple scales as well as bioinformatics information on levels of protein expression and other data. We can populate cytoplasm, membranes, and organelles within the same structural volume to generate cellular environments that synthesize our current knowledge
of such systems.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><span lang="FR" style="font-size:11.0pt;font-family:"Arial","sans-serif"">The communication of complex structural information requires extensive scientific knowledge as well as expertise in creating clear visualizations.
We have developed a method of combining scientific modeling environments with professional grade 3D modeling and animation programs such as Maya, Cinema4D and Blender. This gives both scientists and professional illustrators access to the best tools to communicate
the science and the art of the molecular cell.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><span lang="FR" style="font-size:11.0pt;font-family:"Arial","sans-serif"">Gillet, A., Sanner, M., Stoffler, D., Olson, A.J. (2005) Tangible interfaces for structural molecular biology. Structure:13:483-491.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><span lang="FR" style="font-size:11.0pt;font-family:"Arial","sans-serif";color:black">Johnson, G.T., Autin, L., Goodsell, D.S., Sanner, M.F., Olson A.J. (2011)
</span><i><span lang="FR" style="font-size:11.0pt;font-family:"Arial","sans-serif"">ePMV</span></i><span lang="FR" style="font-size:11.0pt;font-family:"Arial","sans-serif""> Embeds Molecular Modeling into Professional Animation Software Environments. Structure
19(3):293-303.<o:p></o:p></span></p>
<p class="MsoNormal"><b><span lang="FR" style="font-size:14.0pt;font-family:"Verdana","sans-serif""><o:p> </o:p></span></b></p>
<p class="MsoNormal"><b><span lang="FR" style="font-size:14.0pt;font-family:"Verdana","sans-serif"">Vljudno vabljeni! / Kindly invited!<o:p></o:p></span></b></p>
<p class="MsoNormal"><span lang="FR"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="FR" style="font-family:"Arial","sans-serif"">Več informacij v priponki / more information attached<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="FR" style="color:#1F497D">***</span><span lang="FR"><o:p></o:p></span></p>
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