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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal>Vabimo vas na 1. predavanje iz sklopa "Kolokviji na IJS" v letu 2012/13, ki bo <strong><span style='color:red'>v četrtek, 20. septembra 2012, ob 11. uri </span></strong><span style='color:red'>v Veliki predavalnici Instituta »Jožef Stefan«</span> na Jamovi cesti 39 v Ljubljani. Napovednik predavanja najdete tudi na naslovu <a href="http://www.ijs.si/ijsw/Koledar_prireditev">http://www.ijs.si/ijsw/Koledar_prireditev</a>, posnetke preteklih predavanj<span style='color:blue'> </span>pa na <a href="http://videolectures.net/kolokviji_ijs">http://videolectures.net/kolokviji_ijs</a>. <o:p></o:p></p><p class=MsoNormal>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~<br><br><o:p></o:p></p><p class=MsoNormal><b>prof. dr. M. Muthukumar<o:p></o:p></b></p><p class=MsoNormal><i>University of Massachusetts, Amherst, ZDA<o:p></o:p></i></p><p class=MsoNormal style='mso-margin-top-alt:auto;text-align:justify'><b><span style='font-size:14.0pt;mso-fareast-language:SL'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-size:14.0pt'>Teorija makromolekularnega transporta skozi proteinske kanale in nanopore</span></b><i><o:p></o:p></i></p><p class=MsoNormal style='text-align:justify'><span lang=SL style='font-size:11.0pt;font-family:"Arial","sans-serif";mso-fareast-language:SL'><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=SL>Razumevanje vseprisotnega pojava translokacije nabitih makromolekul skozi ozke kanale zahteva ustrezen opis dinamike polielektrolitov in elektrolitov ter hidrodinamike in učinka ograditve nabite pore. Biofiziko procesa translokacije polielektrolitov bomo predstavili s koncepti iz fizike polielektrolitov in elektrofiziologije ter z eksperimentalnimi študijami na ravni posameznih molekul. Posebej se bomo posvetili zajemu in pomikanju DNA, RNA in proteinov skozi alfa-hemolizinske kanale in trdne nanopore v zunanjem električnem polju kakor tudi iztisku DNA iz bakteriofagov.</span><i><span lang=SL><o:p></o:p></span></i></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt;text-align:justify'>Predavanje bo v angleščini.<span style='mso-fareast-language:SL'><o:p></o:p></span></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt'><strong><span style='color:red'>Lepo vabljeni!<o:p></o:p></span></strong></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt'><strong><span style='font-weight:normal'><o:p> </o:p></span></strong></p><p class=MsoNormal align=center style='text-align:center'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>*****<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><o:p> </o:p></p><p class=MsoNormal style='text-align:justify'><o:p> </o:p></p><p class=MsoNormal style='text-align:justify'>We would like to invite you to the 1st lecture of the "Kolokviji na IJS" in the school year 2012/13. The lecture will be held <b>on Thursday, September 20, 2012, at 11 am</b> at the <b>JSI main lecture hall</b>, Jamova 39, Ljubljana. The abstract of the lecture can be found on website: <span style='font-size:10.0pt'><a href="http://www.ijs.si/ijsw/Koledar_prireditev"><span style='font-size:12.0pt'>http://www.ijs.si/ijsw/Koledar_prireditev</span></a></span>, the previous recorded lectures can be found on website: <span style='font-size:10.0pt'><a href="http://videolectures.net/kolokviji_ijs"><span style='font-size:12.0pt'>http://videolectures.net/kolokviji_ijs</span></a></span>.<span style='font-size:10.0pt'> </span><o:p></o:p></p><p class=MsoNormal>********************************************<br><br><b><span lang=SL><o:p></o:p></span></b></p><p class=MsoNormal><b>prof. dr. M. Muthukumar<o:p></o:p></b></p><p class=MsoNormal><i>University of Massachusetts, Amherst, USA<o:p></o:p></i></p><p class=MsoNormal><b><span style='font-size:16.0pt;mso-fareast-language:SL'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-size:16.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-size:16.0pt'>Theory of macromolecular transport through protein channels and nanopores<o:p></o:p></span></b></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal style='text-align:justify'>An understanding of the ubiquitous phenomenon of translocation of electrically charged macromolecules through narrow channels requires an adequate description of polyelectrolyte dynamics, electrolyte dynamics, and hydrodynamics, and the confinement effects from the charge-decorated pores. The biophysics of polyelectrolyte translocation process will be discussed using concepts from polyelectrolyte physics and electrophysiology, against a background of single-molecule experiments. Specifically, the capture and threading of DNA/RNA and proteins through alpha-hemolysin channels and solid-state nanopores under an external electric field, and DNA ejection in bacteriophages will be discussed..<o:p></o:p></p><p class=MsoNormal style='text-align:justify'><o:p> </o:p></p><p class=MsoNormal><b><span style='font-size:14.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-size:14.0pt'>We look forward to meeting you at the “Kolokvij na IJS”!<o:p></o:p></span></b></p><p class=MsoNormal align=center style='text-align:center'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p></div></body></html>