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</o:shapelayout></xml><![endif]--></head><body lang=SL link=blue vlink=purple><div class=WordSection1><p class=MsoNormal>Vabimo vas na 6. predavanje iz sklopa "Kolokviji na IJS" v letu 2011/12, ki bo <strong><span style='color:red'>v sredo, 2. novembra, 2011, ob 13. uri </span></strong><span style='color:red'>v Veliki predavalnici Instituta »Jožef Stefan«</span> na Jamovi cesti 39 v Ljubljani. Napovednik predavanja najdete tudi na naslovu <a href="http://www.ijs.si/ijsw/Koledar_prireditev">http://www.ijs.si/ijsw/Koledar_prireditev</a>, posnetke preteklih predavanj<span style='color:blue'> </span>pa na <a href="http://videolectures.net/kolokviji_ijs">http://videolectures.net/kolokviji_ijs</a>. <o:p></o:p></p><p class=MsoNormal style='margin-bottom:12.0pt'>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~<o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><b><span style='mso-fareast-language:ZH-CN'>Prof. dr. Sean Fain<o:p></o:p></span></b></p><p class=MsoNormal><i><span style='mso-fareast-language:ZH-CN'>University of Wisconsin – Madison<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='mso-fareast-language:ZH-CN'>Madison, USA<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='mso-fareast-language:ZH-CN'><o:p> </o:p></span></i></p><p class=MsoNormal><b><span style='font-size:14.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal style='text-align:justify'><b><span style='font-size:14.0pt'>Metode in uporaba magnetno-resonančnega slikanja s hiperpolariziranimi C-13 in H-3 kontrastnimi agenti<o:p></o:p></span></b></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt;text-align:justify'>Nedavne inovacije pri polarizaciji žlahtnih plinov in biološko aktivnih trdnih spojin (na primer 13C-pyrovate) so omogočile nova področja uporabe MRI tehnike za študij funkcionalnih parametrov, kot je na primer metabolizem rakavih celic. Te metode so postavile nove višje zahteve pri hitrosti zajemanja podatkov ter občutljivosti detekcijskih tuljav, da bi lahko učinkovito obravnavali neravnovesno spin-mrežno relaksacijo uporabljenih agentov. V predavanju bo predstavljena osnovna tehnika polarizacije plinov ter najnovejše metode, ki omogočajo doseganje še višjih stopenj polarizacije. Predstavljene bodo tudi posebne metode polarizacijsko ojačane MRI za študij delovanja pljuč ter metabolizma.. <o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt;text-align:justify'>Predavanje bo v angleščini.<o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt'><strong><span style='color:red'>Lepo vabljeni!</span></strong><strong><span style='font-weight:normal'><o:p></o:p></span></strong></p><p class=MsoNormal style='text-align:justify'><span lang=EN-US style='color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>***<o:p></o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-US>We would like to invite you to 6th lecture of the "Kolokvij na IJS" in the school year 2011/12. The lecture will be held <b>on Wednesday, November 2, 2011, at 1 pm</b> at the <b>JSI main lecture hall</b>, Jamova 39, Ljubljana. The abstract of the lecture can be found on website: </span><span lang=EN-US style='font-size:10.0pt'><a href="http://www.ijs.si/ijsw/Koledar_prireditev"><span style='font-size:12.0pt'>http://www.ijs.si/ijsw/Koledar_prireditev</span></a></span><span lang=EN-US>, the previous recorded lectures can be found on website: </span><span lang=EN-US style='font-size:10.0pt'><a href="http://videolectures.net/kolokviji_ijs"><span style='font-size:12.0pt'>http://videolectures.net/kolokviji_ijs</span></a></span><span lang=EN-US>.</span><span lang=EN-US style='font-size:10.0pt'> </span><span lang=EN-US><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span lang=EN-US>********************************************</span><b><span style='mso-fareast-language:ZH-CN'><o:p></o:p></span></b></p><p class=MsoNormal><b><span style='mso-fareast-language:ZH-CN'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='mso-fareast-language:ZH-CN'>Prof.dr. Sean Fain<o:p></o:p></span></b></p><p class=MsoNormal><i><span style='mso-fareast-language:ZH-CN'>University of Wisconsin – Madison<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='mso-fareast-language:ZH-CN'>Madison, USA<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='mso-fareast-language:ZH-CN'><o:p> </o:p></span></i></p><p class=MsoNormal><b><span lang=EN-US style='font-size:16.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span lang=EN-US style='font-size:16.0pt'>Methodology and applications of magnetic resonance imaging (MRI) with hyperpolarized C-13 and He-3 contrast agents<o:p></o:p></span></b></p><p class=MsoNormal><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal><span lang=EN-US>Recent innovations in polarization of noble gases and solid state biologically active compounds such as <sup>13</sup>C-pyruvate have enable new applications of MRI for the study of functional parameters such as lung ventilation and cancer metabolism. These methods have put increase demands on acquisition speed and rf-coil sensitivity in order to address the non-equilibrium spin-lattice (T<sub>1</sub>) decay of these agents and multi-nuclear nature of the signal detection problem, e.g. imaging conventional proton and the polarized nucleus either sequentially or simultaneously. This talk will introduce the methodology behind polarization and methods to improve polarization levels and image quality using dual-tuned coil designs and fast MRI methods. Several applications of polarized MRI to study lung function and metabolism will be presented.<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal><b><span lang=EN-US style='font-size:14.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span lang=EN-US style='font-size:14.0pt'>We look forward to meeting you at the “Kolokvij na IJS”!<o:p></o:p></span></b></p><p class=MsoNormal><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p></div></body></html>